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Related Experiment Video

Updated: May 20, 2026

The Influence of Liver Resection on Intrahepatic Tumor Growth

The Influence of Liver Resection on Intrahepatic Tumor Growth

Published on: April 9, 2016

Malignant liver tumors.

Joshua N Honeyman¹, Michael P La Quaglia

¹Pediatric Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York 10065, USA.

Seminars in Pediatric Surgery

|July 18, 2012

Summary

Pediatric liver cancers are rare but serious. Advances in systemic therapy, surgery, and liver transplantation have improved treatment outcomes for these malignant tumors.

Area of Science:

Pediatric Oncology
Hepatobiliary Malignancies

Background:

Malignant liver tumors represent a small proportion of childhood cancers.
These cancers are a significant cause of illness and death in children.
Recent decades have seen substantial progress in managing pediatric liver malignancies.

Purpose of the Study:

To review the staging and treatment of prevalent malignant liver tumors in pediatric patients.
To highlight therapeutic advancements in the management of pediatric liver cancer.

Main Methods:

Literature review of recent advancements in pediatric liver cancer treatment.
Discussion of current staging systems for liver malignancies.
Analysis of surgical and systemic therapy approaches.

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Murine Model of Metastatic Liver Tumors in the Setting of Ischemia Reperfusion Injury

Murine Model of Metastatic Liver Tumors in the Setting of Ischemia Reperfusion Injury

Published on: August 30, 2019

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Last Updated: May 20, 2026

The Influence of Liver Resection on Intrahepatic Tumor Growth

The Influence of Liver Resection on Intrahepatic Tumor Growth

Published on: April 9, 2016

Murine Model of Metastatic Liver Tumors in the Setting of Ischemia Reperfusion Injury

Murine Model of Metastatic Liver Tumors in the Setting of Ischemia Reperfusion Injury

Published on: August 30, 2019

Main Results:

Significant therapeutic gains have been achieved through improved systemic therapies and surgical interventions.
Enhanced liver transplantation techniques enable complete resection even in advanced disease.
Current management strategies offer improved survival rates for pediatric liver cancer.

Conclusions:

Pediatric liver tumors, while uncommon, require specialized management.
Multidisciplinary approaches combining surgery, transplantation, and systemic therapy are crucial.
Continued research is vital to further improve outcomes for children with liver cancer.