Related Experiment Video
Updated: Aug 15, 2026

Design of Cecal Ligation and Puncture and Intranasal Infection Dual Model of Sepsis-Induced Immunosuppression
Published on: June 15, 2019
Septic shock and death due to occult sinusitis
1Centre for Audiology, Education of the Deaf & Speech Pathology, University of Manchester.
Abstract:
We report a case of septicaemia and death due to occult sinusitis in an otherwise healthy adult. Septicaemia was diagnosed on clinical grounds and blood culture grew Streptococcus pneumoniae. Maxillary sinusitis was discovered incidentally on a CT scan four days after the onset of symptoms. A sinus wash-out revealed pus which on culture was positive for Streptococcus pneumoniae. The patient deteriorated gradually and died despite appropriate therapy. We conclude that sinusitis should be suspected in any case of septicaemia where the primary focus is not known and the patient does not respond quickly to treatment.
Related Concept Videos
Inhalation Anthrax
Cryptococcal Meningitis
Bacterial Meningitis I: Introduction
Bacterial Meningitis II: Pathophysiology
Brain Abscess l: Introduction
Intestinal Obstruction II: Pathophysiology

