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Updated: May 20, 2026

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
07:54

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea

Published on: December 6, 2016

Drug-induced sleep endoscopy in persistent pediatric sleep-disordered breathing after adenotonsillectomy

Megan L Durr1, Anna K Meyer, Eric J Kezirian

  • 1Department of Otolaryngology–Head and Neck Surgery, University of California, San Francisco, USA. mdurr@ohns.ucsf.edu

Archives of Otolaryngology--Head & Neck Surgery
|July 18, 2012
PubMed

Insights

Drug-induced sleep endoscopy (DISE) is feasible in children with persistent sleep-disordered breathing (SDB) after surgery. DISE identified multilevel airway obstruction, often due to tongue base issues or regrowth, indicating multiple factors contribute to SDB in these pediatric patients.

Area of Science:

  • Pediatric Otolaryngology
  • Sleep Medicine
  • Airway Imaging

Background:

  • Sleep-disordered breathing (SDB) can persist in children even after tonsillectomy and adenoidectomy (T&A).
  • Identifying the specific causes of persistent SDB is crucial for effective treatment.

Purpose of the Study:

  • To assess the feasibility of performing drug-induced sleep endoscopy (DISE) in pediatric patients.
  • To analyze the findings of DISE in children experiencing persistent SDB post-T&A.

Main Methods:

  • Retrospective case series involving a review of medical charts.
  • Drug-induced sleep endoscopy (DISE) was performed on thirteen pediatric subjects with persistent SDB after T&A.
  • Documentation of all sites of upper airway obstruction was recorded.

Main Results:

  • Multilevel upper airway obstruction was observed in most pediatric patients.
  • Common sites of obstruction included the tongue base, adenoid regrowth, and inferior turbinate hypertrophy.
  • No significant differences were found among the analyzed subgroups.

Conclusions:

  • DISE is a feasible procedure for evaluating pediatric patients with persistent SDB after T&A.
  • Multiple anatomical factors contribute to persistent SDB in this population.
  • Further research is warranted to explore targeted surgical interventions for improved outcomes.
Abstract

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