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A case of mistaken identity: subacute bacterial endocarditis associated with p-antineutrophil cytoplasmic antibody

A M Riding1, D P D'Cruz

  • 1The Louise Coote Lupus Unit, Guys and St Thomas Hospital NHS Foundation Trust, UK. alexriding@doctors.org.uk

BMJ Case Reports
|July 18, 2012
PubMed

Insights

This study reports a rare case of subacute bacterial endocarditis (SBE) in a patient with only p-ANCA positive antibodies. Early identification of antineutrophil cytoplasmic antibodies (ANCAs) is crucial for differentiating infection from vasculitis.

Area of Science:

  • Immunology
  • Infectious Diseases
  • Cardiology

Background:

  • Subacute bacterial endocarditis (SBE) is a serious infection of the heart valves.
  • Antineutrophil cytoplasmic antibodies (ANCAs) are typically associated with autoimmune vasculitis but can also be linked to infections.
  • Previous reports of SBE associated with ANCAs predominantly involve c-ANCA positivity.

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