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Updated: May 20, 2026
10:19
A Murine Model of Group B Streptococcus Vaginal Colonization
Published on: November 16, 2016
Late onset group B streptococcal disease manifests as submandibular cellulitis
1Department of Paediatrics, Royal Bolton Hospital, Bolton, UK. shettysandeep93@yahoo.co.in
BMJ Case Reports
|July 18, 2012
Summary
A six-week-old infant presented with inconsolable crying and fever. Group B Streptococcus (GBS) infection was diagnosed, causing submandibular swelling and successfully treated with antibiotics.
Area of Science:
- Neonatal Medicine
- Pediatric Infectious Diseases
- Bacteriology
Background:
- Group B Streptococcus (GBS) is a significant cause of neonatal infections.
- Early-onset GBS disease typically manifests within the first week of life.
- Late-onset GBS disease can occur up to 90 days postpartum.
Observation:
- A 6-week-old male infant presented with acute onset of inconsolable crying and pyrexia.
- Clinical examination revealed a tender submandibular swelling.
- Initial investigations, including imaging, were non-specific, but C-reactive protein (CRP) levels significantly elevated.
Findings:
- Blood cultures confirmed the presence of Group B Streptococcus (GBS).
- The infant's presentation was consistent with late-onset GBS infection.
- Prompt antibiotic treatment led to full recovery.
Implications:
- This case highlights the importance of considering GBS infection in infants presenting with non-specific symptoms like fever and irritability, even without typical risk factors.
- Timely diagnosis and appropriate antibiotic therapy are crucial for favorable outcomes in late-onset GBS disease.
- Raising awareness among healthcare providers about the varied presentations of GBS infection in infants is essential for early detection and management.
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