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Updated: May 20, 2026

Double Direct Injection of Blood into the Cisterna Magna as a Model of Subarachnoid Hemorrhage
Published on: August 30, 2020
Subarachnoid haemorrhage in undiagnosed secondary hypertension: back to basics
Muhammad Ahsan Saleem1, Oliver A Leach, Thomas David Miller
1Department of Neuroradiology, Western General Hospital, University of Edinburgh, Edinburgh, Midlothian, UK. dr_ahsan@yahoo.com
Insights
Undiagnosed aortic coarctation can lead to serious complications like subarachnoid hemorrhage from intracerebral aneurysms. Early diagnosis and treatment are crucial for managing secondary hypertension and preventing life-threatening events.
Area of Science:
- Cardiology
- Neurology
- Radiology
Background:
- Aortic coarctation (AC) is a congenital heart defect often diagnosed in childhood, but mild or moderate cases can remain undetected into adulthood.
- Undiagnosed AC can lead to severe hypertension and associated complications, significantly impacting patient health.
- Secondary hypertension in adults warrants thorough investigation for underlying causes, including congenital abnormalities.
Observation:
- A 20-year-old woman with a history of severe hypertension presented with sudden-onset headache.
- Cerebral CT revealed subarachnoid hemorrhage (SAH), attributed to two intracerebral aneurysms.
- Weak femoral pulses during attempted catheterization led to the discovery of significant aortic coarctation.
Findings:
- The patient's severe hypertension was found to be secondary to undiagnosed aortic coarctation.
- Subarachnoid hemorrhage was caused by intracerebral aneurysms, a known complication of severe hypertension.
- Successful endovascular coiling of the aneurysms was performed.
Implications:
- This case highlights the importance of considering aortic coarctation in young adults with severe, unexplained hypertension.
- Delayed diagnosis of AC can lead to life-threatening neurological complications such as aneurysmal SAH.
- Comprehensive vascular imaging and assessment are essential in patients with secondary hypertension and neurological events.
Abstract:
Aortic coarctation (AC) is a significant cause of secondary hypertension and is diagnosed in childhood in the vast majority of patients. Mild or moderate coarctation may exist undetected into adult life, when it usually presents due to its sequelae. The authors present the case of a 20-year-old woman, previously extensively investigated for severe hypertension, who was admitted following sever, sudden-onset headache. CT scanning of the head showed the presence of subarachnoid blood (SAH), with subsequent CT angiography revealing two intracerebral aneurysms as the source. On attempting to catheterise the femoral artery her pulses were noted to be weak and during passage of the catheter she was found to have significant AC. The aneurysms were duly treated with detachable coils and the clinical course with regard to the SAH was unremarkably safe for high-pressure headache.
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