Related Experiment Video
Updated: May 20, 2026

07:06
Block Building Task Identifies Distinct Groups of Left/Right-hand Choice Patterns After Unilateral Peripheral Nerve Injury
Published on: March 21, 2025
Posterior alien hand in a left-handed person
Emanuela Terazzi1, Daniela Mittino, Francesco Monaco
1Clinica Neurologica, AOU Maggiore della Carità, Novara, Italy. terryela@libero.it
BMJ Case Reports
|July 18, 2012
Summary
Posterior alien hand syndrome typically affects the non-dominant hand. This study details the first reported case in a left-handed individual, involving their dominant hand.
Area of Science:
- Neuroscience
- Neurology
- Clinical Case Studies
Background:
- Posterior alien hand syndrome (AHS) is a rare neurological disorder characterized by a limb that moves autonomously.
- It is typically associated with lesions in the contralateral hemisphere, usually the right hemisphere in right-handed individuals.
Observation:
- This report presents a unique case of AHS in a left-handed patient.
- The affected limb was the dominant hand, which is atypical for this condition.
Findings:
- The case demonstrates that AHS can involve the dominant hand in left-handed individuals.
- This challenges the conventional understanding of hemispheric lateralization and its role in AHS.
Implications:
- Findings suggest a need to reconsider the typical hemispheric localization for AHS, especially in non-right-handed populations.
- This case expands the clinical spectrum of alien hand syndrome and its neuroanatomical correlates.
Related Concept Videos
Lateralization
Brain lateralization refers to the division of mental processes and functions between the two hemispheres of the brain, a phenomenon that optimizes neural efficiency and underpins complex abilities in humans. This specialization allows each hemisphere to perform tasks where it has a comparative advantage, facilitating more refined cognitive capabilities across different domains.
Muscles of the Forearm that Move the Hand and Fingers
The muscles of the forearm that move the wrist, hand, and digits are numerous and diverse. They can be classified into two groups based on their location and function — the anterior and posterior compartment muscles.
Anterior Compartment
The anterior compartment muscles originate from the humerus. They primarily function as flexors and are also known as flexor muscles. They typically insert on the carpals, metacarpals, and phalanges. The superficial layer includes the flexor carpi radialis,...
Anterior Compartment
The anterior compartment muscles originate from the humerus. They primarily function as flexors and are also known as flexor muscles. They typically insert on the carpals, metacarpals, and phalanges. The superficial layer includes the flexor carpi radialis,...
Spinal Nerves: Plexus I
Nerve plexuses are networks of interlacing nerves that serve as communication hubs to distribute and organize nerve action across various body regions. The nerve plexuses are organized into the cervical plexus located in the neck region, brachial plexus in the shoulder area, lumbar plexus found in the lower back, sacral plexus situated in the pelvis, and coccygeal plexus located in the coccygeal region.
The Cervical Plexus
The cervical plexus, formed by the anterior rami of the first four...
The Cervical Plexus
The cervical plexus, formed by the anterior rami of the first four...
Somatosensation
The somatosensory system relays sensory information from the skin, mucous membranes, limbs, and joints. Somatosensation is more familiarly known as the sense of touch. A typical somatosensory pathway includes three types of long neurons: primary, secondary, and tertiary. Primary neurons have cell bodies located near the spinal cord in groups of neurons called dorsal root ganglia. The sensory neurons of ganglia innervate designated areas of skin called dermatomes.
Bones of the Upper Limb: Humerus
The upper limb consists of the arm, forearm, wrist, and hand bones. The humerus is the single bone of the upper arm region. Proximally, it has a large, spherical, smooth head that articulates with the glenoid cavity of the scapula to form the glenohumeral or shoulder joint. The margin of the head is the anatomical neck, a residual epiphyseal plate. Laterally it extends to form bony projections called the greater tubercle and the lesser tubercle. Next to the tubercles is the surgical neck, a...
Muscles that Move the Forearm
The muscles that move the forearms can be divided into four groups: forearm flexors, forearm extensors, forearm pronators, and forearm supinators. The flexors and extensors act on the elbow joint, while the pronators and supinators act on the radioulnar joints.
Forearm Flexors
The biceps brachii, brachialis, and brachioradialis are forearm flexors. The biceps brachii is made up of two heads. Its long head originates at the supraglenoid tubercle of the scapula, whereas that of the short head is...
Forearm Flexors
The biceps brachii, brachialis, and brachioradialis are forearm flexors. The biceps brachii is made up of two heads. Its long head originates at the supraglenoid tubercle of the scapula, whereas that of the short head is...

