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Updated: May 20, 2026

Realistic Membrane Modeling Using Complex Lipid Mixtures in Simulation Studies
Published on: September 1, 2023
Chirality and homochirality of lipids is necessary to form LD-supramolecular structures of cell-cell communications
1N. N. Semenov Institute of Chemical Physics, Russian Academy of Sciences, Moscow, Russia. s.stovbun@chph.ras.ru
Abstract:
The processes of cell-cell commutations via anisometric supramolecular structures (strings) in vitro and in physicochemical models of lipids (trifluoroacetylated amino alcohols) were studied. It was shown that biological commutation through strings is more efficient than the diffusion mechanism of transfer of bioactive molecules at distances typical of populations. Strings kinetics was constructed and the signal turnover rate in these systems was evaluated. It was demonstrated that the condition of chirality of lipids forming the cell biomembrane stems from experimentally observed cell commutation through anisometric supramolecular structures.
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