Effects of Prolyl-Glycyl-Proline (PGP) peptide on disorders in rat mesenteric lymphatic vessel function induced by injection of substance 48/80
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B A Umarova1, N S Bondarenko, T V Lelekova
1Department of Human and Animal Physiology, M. V. Lomonosov Moscow State University, Russia. bellaum@mail.ru
Bulletin of Experimental Biology and Medicine
|July 18, 2012
Abstract:
Injection of substance 48/80 to rats led to dysfunction of mesenteric lymphatic microvessels, in particular inhibition of their contractility and modification of their reaction to norepinephrine. Injection of PGP peptide before and after substance 48/80 alleviated these disorders. The results indicated the possibility of peptide correction of lymphatic vessel dysfunction.
