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Hypertension: management perspectives

Claudio Borghi1, Arrigo F G Cicero

  • 1University of Bologna, Internal medicine, Aging and Kidney Diseases Department, Bologna, Italy. claudio.borghi@unibo.it

Expert Opinion on Pharmacotherapy
|July 19, 2012
PubMed

Insights

Future hypertension management will integrate personalized therapies and genetic insights for better blood pressure control. Innovative drugs, particularly renin-angiotensin-aldosterone system modulators, show promise for effective treatment.

Area of Science:

  • Cardiovascular Medicine
  • Pharmacology

Background:

  • Rising global hypertension prevalence necessitates improved blood pressure (BP) control strategies.
  • Associated costs of diagnosis, management, and adverse outcomes strain healthcare systems.

Purpose of the Study:

  • To explore future perspectives in high blood pressure management.
  • To discuss advancements in individualized therapy, genetic contributions, and drug development for hypertension.

Main Methods:

  • Review of current knowledge and recent diagnostic/therapeutic achievements.
  • Discussion of individualized therapy approaches.
  • Examination of genetic factors in hypertension development and control.
  • Analysis of new antihypertensive drug development pipelines.

Main Results:

  • Integration of knowledge and advancements will enable early detection and diagnosis.
  • Individualized and effective treatment strategies are anticipated.
  • Innovative renin-angiotensin-aldosterone system modulators are the most promising drugs in development.

Conclusions:

  • Personalized approaches combined with advanced diagnostics will improve hypertension prevention and treatment.
  • Renin-angiotensin-aldosterone system modulators represent a key area for future antihypertensive drug development.
  • Other drug classes like renalase analogs and endothelin antagonists face developmental or safety challenges.
Abstract

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