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Hypertension: management perspectives
Claudio Borghi1, Arrigo F G Cicero
1University of Bologna, Internal medicine, Aging and Kidney Diseases Department, Bologna, Italy. claudio.borghi@unibo.it
Expert Opinion on Pharmacotherapy
|July 19, 2012
Summary
Future hypertension management will integrate personalized therapies and genetic insights for better blood pressure control. Innovative drugs, particularly renin-angiotensin-aldosterone system modulators, show promise for effective treatment.
Area of Science:
- Cardiovascular Medicine
- Pharmacology
Background:
- Rising global hypertension prevalence necessitates improved blood pressure (BP) control strategies.
- Associated costs of diagnosis, management, and adverse outcomes strain healthcare systems.
Purpose of the Study:
- To explore future perspectives in high blood pressure management.
- To discuss advancements in individualized therapy, genetic contributions, and drug development for hypertension.
Main Methods:
- Review of current knowledge and recent diagnostic/therapeutic achievements.
- Discussion of individualized therapy approaches.
- Examination of genetic factors in hypertension development and control.
- Analysis of new antihypertensive drug development pipelines.
Main Results:
- Integration of knowledge and advancements will enable early detection and diagnosis.
- Individualized and effective treatment strategies are anticipated.
- Innovative renin-angiotensin-aldosterone system modulators are the most promising drugs in development.
Conclusions:
- Personalized approaches combined with advanced diagnostics will improve hypertension prevention and treatment.
- Renin-angiotensin-aldosterone system modulators represent a key area for future antihypertensive drug development.
- Other drug classes like renalase analogs and endothelin antagonists face developmental or safety challenges.
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