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Updated: May 20, 2026

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
Published on: January 17, 2018
Rapidly progressing giant invasive prolactinoma
R H Care1, V S Sunkaraneni, J Theaker
1ENT, Christchurch Hospital, Addington, New Zealand. rachelcare@doctors.net.uk
Objective:
We report an extremely rare case of a giant invasive prolactinoma presenting as a nasopharyngeal tumour.
Method:
Case report and literature review regarding giant prolactinoma.
Results:
Giant prolactinoma is a rare form of prolactinoma which accounts for 0.5-4.4 per cent of all pituitary tumours. It is more common in men and generally presents with symptoms of endocrine disturbance or neurological deficit.
Conclusion:
To our knowledge, this is the first report of giant prolactinoma presenting with symptoms of sinusitis and nasopharyngeal tumour.
