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Updated: May 20, 2026

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High-throughput Fluorometric Measurement of Potential Soil Extracellular Enzyme Activities
Published on: November 15, 2013
[Not Available]
F Borie1, M El Nasser, A Herrero
1Service de chirurgie digestive B, CHU Carémeau - Nîmes.; Registre des tumeurs de l'Hérault - Montpellier.
Journal De Chirurgie
|July 19, 2012
Summary
French consensus guidelines moderately impacted colorectal cancer management. While post-operative mortality and resection rates remained stable, chemotherapy use for advanced colon cancer increased, and lymph node examination improved.
Area of Science:
- Oncology
- Public Health
- Clinical Practice Guidelines
Context:
- Colorectal cancer (CRC) management in France.
- Implementation of national consensus guidelines for rectal cancer (1994) and colonic cancer (1998).
Purpose:
- To evaluate the impact of French consensus guidelines on the management of colonic cancer (CC) and rectal cancer (RC).
- To compare CRC management practices before and after the guideline implementation.
Summary:
- A population-based study analyzed CRC cases from 1992 and 2000.
- Key metrics assessed included post-operative mortality, disease stage at diagnosis, resection rates, lymph node examination, chemotherapy, and radiotherapy use.
- For CC, lymph node examination significantly improved (11% to 27%), and chemotherapy use increased for Dukes stages C and D.
- For RC, preoperative radiotherapy use increased (63% to 75%), but adjuvant radiotherapy use showed no significant change.
Impact:
- The consensus guidelines demonstrated a moderate influence on clinical practices for colorectal cancer.
- Improvements were noted in lymph node evaluation and chemotherapy administration for colon cancer.
- Further dissemination of guidelines and systematic practice evaluation are recommended to enhance their impact on patient outcomes.

