[Assessment of the effects of administering a saline solution flush after contrast medium injection using different...

The purpose of administering a saline solution flush after contrast medium injection is to more effectively utilize the contrast medium remaining in the vessels from the subclavian vein to the superior vena cava. In order to investigate the effects of administering a saline solution flush after a contrast medium injection, we evaluated the effects of various contrast medium injection durations and injection methods on the time-density curve (TDC) using a custom-made TDC measurement phantom. The TDC was found to have a biphasic appearance, showing a rapid increase after the arrival of contrast medium in the target region followed by a slower increase from an inflection point at 25 s after the start of contrast medium injection, reflecting the differences in circulatory dynamics for each duration. The results showed that the effect of saline solution flush was allowed the differences by contrast medium duration at the inflection point. Specifically, when the saline solution flush was administered before the inflection point, the CT number was increased, and when it was administered after the inflection point, contrast enhancement was prolonged. With regard to the method in which the saline solution flush is administered before the inflection point, it was found that injecting a mixture of contrast medium and saline solution before the saline solution flush reduced the degree of inflection of the TDC, resulting in a more stable TDC.