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Mid-upper-arm-circumference and mid-upper-arm circumference z-score: the best predictor of mortality?
J Rasmussen1, A Andersen, A B Fisker
1Bandim Health Project, Indepth Network, Apartado 861, Bissau, Guinea-Bissau. jurasmussen@gmail.com
Insights
Mid-upper-arm circumference (MUAC) effectively identifies children at high risk of mortality, similar to the MUAC z-score. Given its simplicity, MUAC is recommended for field use in assessing child malnutrition and mortality risk.
Area of Science:
- Pediatric Nutrition
- Global Health
- Child Mortality Studies
Background:
- Mid-upper-arm circumference (MUAC) is a standard anthropometric measure for assessing nutritional status in children over six months.
- The World Health Organization (WHO) introduced the MUAC z-score in 2007 for children over three months.
Purpose of the Study:
- To compare the effectiveness of MUAC and MUAC z-score in identifying children at high risk of short-term mortality.
- To evaluate these indicators in Guinea-Bissau.
Main Methods:
- The Bandim Health Project collected data on MUAC measurements and mortality in children from birth up to three years.
- Two cohorts (1995-96 and 2005-06) were studied to assess prognostic abilities using receiver operating characteristic curves, sensitivity, and positive predictive value.
Main Results:
- MUAC identified more girls and younger children (6-11 months) as malnourished compared to the MUAC z-score.
- Both MUAC and MUAC z-score demonstrated comparable prognostic ability for predicting mortality in children aged 6-35 months.
- Prognostic ability was higher in settings with lower mortality rates, and MUAC showed good performance in the youngest infants.
Conclusions:
- MUAC and MUAC z-score have equivalent prognostic abilities for predicting short-term mortality in children aged 6-35 months.
- Due to its ease of use in field settings, MUAC is sufficient for identifying children at high risk of mortality, negating the need for the MUAC z-score.
Background/Objective:
Mid-upper-arm circumference (MUAC) is a simple method of assessing nutritional status in children above 6 months of age. In 2007 World Health Organization (WHO) introduced a MUAC z-score for children above 3 months of age. We evaluated whether MUAC or MUAC z-score had the best ability to identify children with high short-term mortality risk in Guinea-Bissau.
Subjects/Methods:
The Bandim Health Project visits children 3-monthly until 3 years of age. MUAC is measured and deaths are registered. We studied a high-mortality cohort of children born in 1995-96 and a lower mortality cohort of children born in 2005-06. The prognostic ability of MUAC and MUAC z-score to predict mortality within 1 and 3 months after the MUAC assessment were compared by area under the receiver operating characteristic curve, sensitivity and positive predictive value.
Results:
Compared with MUAC z-score, MUAC identified as malnourished more girls than boys (prevalence ratio (PR)=1.74 (1.52;2.01)) and more children aged 6-11 months than children aged 12-35 months (1.59 (1.38;1.82)). There was no difference in the prognostic ability of MUAC and MUAC z-score to predict mortality for children aged 6-35 months. The prognostic ability was higher when mortality was lower. MUAC performed well in the youngest infants.
Conclusion:
In the age group 6-35 months, MUAC and MUAC z-score had the same prognostic ability to predict short-term mortality. As MUAC is easier to use in field settings, there is no need to use MUAC z-score to identify children with a high-mortality risk.
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