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Published on: February 26, 2013
The economics of atrial fibrillation: a time for review and prioritization
1Stroke and Ageing Research Centre, Department of Medicine, Monash University, Clayton, Victoria, Australia. dominique.cadilhac@monash.edu
Insights
Atrial fibrillation increases stroke risk and severity. New detection and anticoagulant strategies are available, but their cost-effectiveness needs evaluation for optimal stroke prevention resource allocation.
Area of Science:
- Cardiology
- Public Health
- Health Economics
Background:
- Atrial fibrillation is a major cause of ischemic stroke, leading to severe outcomes.
- The global aging population will increase atrial fibrillation prevalence and stroke burden.
- Current anticoagulant use for stroke prevention in atrial fibrillation is often inadequate.
Purpose of the Study:
- To highlight the need for cost-effectiveness analyses of new atrial fibrillation detection and stroke prevention strategies.
- To inform evidence-based decisions on resource allocation for stroke prevention.
- To encourage public health research on atrial fibrillation and stroke prevention.
Main Methods:
- Review of existing evidence on atrial fibrillation prevalence and stroke association.
- Identification of new anticoagulant therapies and population screening tools.
- Assessment of the gap in cost-effectiveness data for novel interventions.
Main Results:
- Atrial fibrillation significantly elevates stroke risk, severity, and mortality.
- New anticoagulants and screening tools offer potential benefits but lack economic evaluation.
- Limited information exists on the cost-effectiveness of these advancements compared to current practices.
Conclusions:
- Effective detection and management of atrial fibrillation are crucial for reducing stroke burden.
- Economic analyses are vital to guide investment in stroke prevention resources.
- Further research is needed to determine the value of new atrial fibrillation management options.
Abstract:
Stroke associated with atrial fibrillation may occur in up to one third of people who experience an ischemic event, and results in greater stroke severity and poorer health outcomes. The ageing population in developed and developing countries will lead to an increase in the prevalence of atrial fibrillation in society. Detecting people who have atrial fibrillation and ensuring optimal prevention management is essential for reducing the burden of stroke worldwide. There is evidence that use of anticoagulants is inadequate in primary and secondary prevention of stroke. New anticoagulants that have fewer side effects and population screening tools are available. However, there is little information available about the cost-effectiveness of these new options for atrial fibrillation detection and stroke prevention management over current practice. Since resources for spending in health are limited, it is essential that formal economic analyses are undertaken to ensure there are informed and evidence-based decisions on where to best invest stroke prevention resources. It is essential that renewed efforts in the area of atrial fibrillation and options for stroke prevention are undertaken within the public health research community.
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