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Computed tomographic and pathological findings of dermatofibrosarcoma protuberans
Xinchun Li1, Weidong Zhang, Lihua Xiao
1Department of Radiology, The First Affiliated Hospital of Guangzhou Medical College, Guangzhou, PR China.
Journal of Computer Assisted Tomography
|July 19, 2012
Summary
Computed tomography (CT) reveals dermatofibrosarcoma protuberans as solitary, superficial masses with varied enhancement patterns. CT imaging aids in determining tumor size, location, and extent, improving diagnostic understanding.
Area of Science:
- Radiology
- Oncology
- Dermatopathology
Background:
- Dermatofibrosarcoma protuberans (DFSP) is a rare, low-grade soft tissue sarcoma.
- Accurate imaging is crucial for diagnosis and surgical planning of DFSP.
Purpose of the Study:
- To correlate computed tomographic (CT) findings with pathological results for DFSP.
- To enhance awareness and understanding of DFSP on CT imaging.
Main Methods:
- Retrospective analysis of CT scans (plain and enhanced) from 16 cases (17 tumors) of pathologically confirmed DFSP.
- Comparison of imaging features with histological and immunohistochemical findings.
Main Results:
- DFSP typically presents as a solitary, superficial subcutaneous mass (mean diameter 4.0 cm).
- Enhancement patterns varied (homogeneous/heterogeneous) with intratumoral degeneration noted.
- Histology showed uniform spindle cells in a storiform pattern, positive for CD34 and vimentin.
Conclusions:
- CT findings of DFSP include superficial solid masses with variable enhancement.
- CT is valuable for assessing tumor size, location, depth, and extent.
- Improved CT interpretation aids in the diagnosis of dermatofibrosarcoma protuberans.
