The transpulmonary thermodilution technique
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Updated: May 20, 2026
Surfactant Depletion Combined with Injurious Ventilation Results in a Reproducible Model of the Acute Respiratory Distress Syndrome (ARDS)
Published on: April 7, 2021
Samir G Sakka1, Daniel A Reuter, Azriel Perel
1Department of Anesthesiology and Operative Intensive Care Medicine, Medical Center Cologne-Merheim, University of Witten/Herdecke, Cologne, Germany. sakkas@kliniken-koeln.de
Abstract:
The transpulmonary thermodilution technique (TPTD) is a safe, multi-parametric advanced cardiopulmonary monitoring technique that provides important parameters required for making decisions in critically ill patients. The TPTD provides more reliable indicators of preload than filling pressures, the unique measurement of extravascular lung water (EVLW) and comparable accuracy in measuring cardiac output (CO). Intermittent measurement of the CO by TPTD when coupled with pulse contour analysis, offer automatic calibration of continuous CO, as well as accurate assessment of volumetric preload, fluid responsiveness and EVLW. TPTD-guided algorithms have been shown to improve the management of high-risk surgical and critically ill patients.
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