Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: May 20, 2026

Flow-assisted Dielectrophoresis: A Low Cost Method for the Fabrication of High Performance Solution-processable Nanowire Devices
09:14

Flow-assisted Dielectrophoresis: A Low Cost Method for the Fabrication of High Performance Solution-processable Nanowire Devices

Published on: December 7, 2017

Nanoscale sensor analysis using the immersed molecular electrokinetic finite element method.

Adrian M Kopacz1, Woon-Hong Yeo, Jae-Hyun Chung

  • 1Department of Mechanical Engineering, Northwestern University, Evanston, IL, USA. a-kopacz@northwestern.edu

Nanoscale
|July 19, 2012
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Advances in wearable sensing technologies and intelligent systems for healthcare and fitness.

Nanoscale horizons·2026
Same author

Low-Effort Respiratory Function Estimation with a Soft Wearable Digital Spirometry Patch.

Biosensors·2026
Same author

Soft, skin-interfaced electronics enable cannula-free wireless monitoring of sleep respiration.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

At-Home Sleep Electroencephalography Assessment in Young and Older Adults Using a Novel Wireless Soft Electronics Sleep Monitoring System: Experimental Study.

JMIR formative research·2026
Same author

Continuous blood pressure monitoring via hemodynamic parameter and pulse transit time derived from capacitive sensing pads.

Physiological measurement·2026
Same author

Wrinkle-Adaptive Kirigami Wearables With Anisotropic Deformability for Sleep EEG Monitoring.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026

Computational study shows single nanowire (SNW) sensors offer higher dielectrophoretic (DEP) forces for molecular concentration than dendritic nanotips (DNTs). Decreasing SNW diameter enhances DEP force and particle retention, crucial for point-of-care diagnostics.

Area of Science:

  • Nanotechnology
  • Biomedical Engineering
  • Computational Physics

Background:

  • Developing point-of-care diagnostic devices faces challenges in molecular biomarker concentration and detection.
  • Electric field-induced concentration methods have shown limited success due to insufficient efficacy.

Purpose of the Study:

  • To computationally investigate the molecular concentration and retention efficacy of single nanowire (SNW) and dendritic nanotip (DNT) sensors.
  • To compare the dielectrophoretic (DEP) force characteristics of SNW and DNT sensors for optimizing biomarker capture.

Main Methods:

  • Computational study simulating dielectrophoretic (DEP) forces on nanoparticles (NPs) near SNW and DNT sensor geometries.
  • Analysis of DEP force magnitude and spatial distribution as a function of sensor dimensions and NP size.

More Related Videos

A Closed-Type Wireless Nanopore Electrode for Analyzing Single Nanoparticles
08:31

A Closed-Type Wireless Nanopore Electrode for Analyzing Single Nanoparticles

Published on: March 20, 2019

Quantitative and Qualitative Examination of Particle-particle Interactions Using Colloidal Probe Nanoscopy
13:15

Quantitative and Qualitative Examination of Particle-particle Interactions Using Colloidal Probe Nanoscopy

Published on: July 18, 2014

Related Experiment Videos

Last Updated: May 20, 2026

Flow-assisted Dielectrophoresis: A Low Cost Method for the Fabrication of High Performance Solution-processable Nanowire Devices
09:14

Flow-assisted Dielectrophoresis: A Low Cost Method for the Fabrication of High Performance Solution-processable Nanowire Devices

Published on: December 7, 2017

A Closed-Type Wireless Nanopore Electrode for Analyzing Single Nanoparticles
08:31

A Closed-Type Wireless Nanopore Electrode for Analyzing Single Nanoparticles

Published on: March 20, 2019

Quantitative and Qualitative Examination of Particle-particle Interactions Using Colloidal Probe Nanoscopy
13:15

Quantitative and Qualitative Examination of Particle-particle Interactions Using Colloidal Probe Nanoscopy

Published on: July 18, 2014

  • Investigation of DEP force efficacy in overcoming Brownian motion for molecular retention.

    • Main Results:

    • SNW sensors generate higher localized DEP forces near the tip compared to DNT sensors.
    • DEP force magnitude on SNWs increases exponentially with decreasing diameter, enhancing NP retention.
    • DNT sensors exhibit improved concentration efficacy over a wider region due to multiple electric field concentration points.

    Conclusions:

    • SNW sensors are effective for concentrating smaller nanoparticles, with efficacy enhanced by reducing nanowire diameter.
    • DNT sensors offer broader efficacy in molecular concentration due to their geometry.
    • Oligonucleotide elongation via DEP force presents a strategy for enhanced concentration and retention in diagnostic applications.