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Related Concept Videos

Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by transmural...
Inflammatory Bowel Disease II: Ulcerative Colitis01:20

Inflammatory Bowel Disease II: Ulcerative Colitis

Ulcerative colitis is a chronic inflammatory disorder of the colon characterized by continuous mucosal inflammation that typically begins in the rectum and extends proximally in a uniform pattern. Its pathogenesis involves a complex interplay of genetic predisposition, immune dysregulation, and environmental influences. These factors converge to impair the colon’s epithelial defenses and promote an exaggerated inflammatory response against luminal contents.Breakdown of the Mucosal BarrierA...
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy

Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the colonic...
Inflammatory Bowel Disease III: Crohn's Disease01:25

Inflammatory Bowel Disease III: Crohn's Disease

Crohn’s disease is a chronic, relapsing form of inflammatory bowel disease characterized by segmental, transmural inflammation that can affect any part of the gastrointestinal tract. Its pathogenesis arises from a combination of genetic susceptibility, environmental exposures, epithelial barrier dysfunction, and immune dysregulation. Together, these factors lead to an exaggerated immune response against components of the gut microbiome.Genetic and Environmental InfluencesMultiple genetic...
Inflammatory Bowel Disease IV: Clinical Manifestations01:20

Inflammatory Bowel Disease IV: Clinical Manifestations

Inflammatory bowel disease (IBD) encompasses two major chronic disorders—ulcerative colitis and Crohn’s disease—each characterized by relapsing episodes of gastrointestinal inflammation. Although they share certain clinical features, their patterns of involvement and manifestations differ in ways that aid diagnosis and guide management.Ulcerative ColitisUlcerative colitis is limited to the colon and rectum and involves continuous inflammation of the mucosal layer. The disease course is marked...

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Updated: May 20, 2026

Tissue Engineering of the Intestine in a Murine Model
08:45

Tissue Engineering of the Intestine in a Murine Model

Published on: December 1, 2012

Recent advances in small bowel diseases: Part II.

Alan B R Thomson1, Angeli Chopra, Michael Tom Clandinin

  • 1Department of Medicine, University of Western Ontario, London, ON N6A 5A5, Canada. athoms47@uwo.ca

World Journal of Gastroenterology
|July 19, 2012
PubMed
Summary
This summary is machine-generated.

Advances in gastroenterology and hepatology knowledge occurred in 2009-2010, particularly concerning small intestinal diseases. This review covers key basic science and clinical findings in absorption, short bowel syndrome, motility, tumors, imaging, and cystic fibrosis.

Keywords:
AbsorptionCystic fibrosisDiagnostic imagingIntestinal motilityShort bowel syndromeSmooth muscle functionTumors

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Last Updated: May 20, 2026

Tissue Engineering of the Intestine in a Murine Model
08:45

Tissue Engineering of the Intestine in a Murine Model

Published on: December 1, 2012

Murine Ileocolic Bowel Resection with Primary Anastomosis
08:49

Murine Ileocolic Bowel Resection with Primary Anastomosis

Published on: October 29, 2014

Small Bowel Transplantation In Mice
36:30

Small Bowel Transplantation In Mice

Published on: August 20, 2007

Area of Science:

  • Gastroenterology and Hepatology
  • Small Intestinal Diseases

Background:

  • Significant advancements in understanding small intestinal diseases occurred in 2009 and 2010.
  • Over 1000 publications were reviewed to identify key developments.

Purpose of the Study:

  • To summarize important advances in basic science and clinical applications related to small intestinal diseases.
  • To review six specific topics in small intestinal research and practice.

Main Methods:

  • Comprehensive literature review of over 1000 publications from 2009-2010.
  • Focus on both fundamental scientific discoveries and practical clinical applications.

Main Results:

  • Key findings in absorption and short bowel syndrome were identified.
  • Advances in smooth muscle function, intestinal motility, tumors, diagnostic imaging, and cystic fibrosis were detailed.

Conclusions:

  • The period of 2009-2010 marked substantial progress in the field of small intestinal diseases.
  • This review provides a consolidated overview of critical updates for clinicians and researchers.