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Updated: May 20, 2026

Preparation and In Vivo Use of an Activity-based Probe for N-acylethanolamine Acid Amidase
Published on: November 23, 2016
2-(1H-Benzimidazol-2-yl)-N-[(E)-(dimethyl-amino)-methyl-idene]benzene-sulfonamide
Abstract:
The asymmetric unit of the title compound, C(16)H(16)N(4)O(2)S, contains two mol-ecules (A and B) with similar conformations: the benzene rings are oriented at dihedral angles of 80.94 (10)° and 84.54 (10)° with their adjacent 1H-benzimidazole groups. In the crystal, the mol-ecules are connected by N-H⋯N hydrogen bonds, forming separate C(4) chains of both the A and B mol-ecules along [010]. The A and B chains are cross-linked by several C-H⋯O inter-actions involving the benzene rings and the sulfonyl groups, which lead to R(2) (1)(5) loops in the linkage of the chains.
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