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Ewing's sarcoma and primitive neuroectodermal tumour (ES/PNET) presenting as a breast mass
Suebwong Chuthapisith1, Wilairat Prasert, Malee Warnnissorn
1Department of Surgery, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand.
Oncology Letters
|July 19, 2012
Summary
This case report details a rare instance of Ewing
Area of Science:
- Oncology
- Pathology
- Genetics
Background:
- Ewing sarcoma/primitive neuroectodermal tumor (ES/PNET) is a rare cancer typically affecting young individuals.
- Breast tissue is an uncommon site for ES/PNET development.
- This report focuses on a 46-year-old female patient diagnosed with ES/PNET in her breast.
Purpose of the Study:
- To present a case of ES/PNET in an adult female breast.
- To discuss the clinical presentation, radiological findings, and diagnostic methods for this rare condition.
- To review existing literature on ES/PNET in the breast.
Main Methods:
- Case report of a 46-year-old female patient with a breast lump.
- Clinical examination and radiological assessment.
- Immunohistochemical studies and genetic analysis for translocation t(11;22) to confirm diagnosis.
- Literature review of similar cases.
Main Results:
- Diagnosis of ES/PNET was confirmed in a 46-year-old female patient.
- Immunohistochemistry and detection of the t(11;22) translocation were key diagnostic findings.
- The case highlights the possibility of ES/PNET occurring in adult breast tissue.
Conclusions:
- Ewing sarcoma/primitive neuroectodermal tumor can rarely occur in adult breast tissue.
- Accurate diagnosis requires a combination of clinical, radiological, immunohistochemical, and genetic evaluations.
- This case contributes to understanding the presentation and diagnosis of rare breast malignancies.
