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The pathophysiology of urinary tract infections (UTIs) encompasses several progressive stages, beginning with bacterial colonization and culminating in potential systemic complications if untreated. UTIs are primarily initiated by bacteria, such as Escherichia coli, which often originate from the gastrointestinal tract and migrate to the urinary system through the periurethral area. This migration can occur via several routes, including improper hygiene practices, sexual activity, or...
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Measurement of Tactile Allodynia in a Murine Model of Bacterial Prostatitis
06:46

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Published on: January 16, 2013

Clinicopathological association between BPH and prostatitis.

A Rijal1, K Gautam

  • 1Department of Surgery, Nepal Medical College Teaching Hospital, Attarkhel, Jorpati, Kathmandu, Nepal. anjan.rijal@gmail.com

Nepal Medical College Journal : NMCJ
|July 20, 2012
PubMed
Summary
This summary is machine-generated.

Differentiating benign prostatic hyperplasia (BPH) and BPH with prostatitis is challenging based on symptoms alone due to significant overlap. Histopathology confirmed prostatitis in nearly half of the BPH patients studied.

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Area of Science:

  • Urology
  • Pathology

Background:

  • Benign prostatic hyperplasia (BPH) is a common condition in aging men.
  • Prostatitis can coexist with BPH, potentially altering clinical presentation.

Purpose of the Study:

  • To investigate the relationship between BPH and BPH with prostatitis.
  • To assess if clinical symptoms can differentiate these two conditions.
  • To correlate symptoms with histopathological findings.

Main Methods:

  • Prospective study of 36 patients undergoing surgery for lower urinary tract symptoms (LUTS) due to BPH.
  • Pre-operative symptom assessment and statistical analysis (odds ratio).
  • Histopathological examination of surgical specimens.

Main Results:

  • Dysuria was the most frequent symptom in BPH with prostatitis, but symptom overlap was substantial.
  • Clinical differentiation between BPH and BPH with prostatitis based on symptoms alone is difficult.
  • Histopathology revealed prostatitis in 19 out of 36 patients (52.8%).
  • The most common prostatitis pattern associated with BPH was stromal inflammation.

Conclusions:

  • Distinguishing BPH from BPH with prostatitis requires a high index of clinical suspicion.
  • Histopathology is crucial for accurate diagnosis of coexisting prostatitis.
  • Stromal inflammatory pattern is the predominant type of prostatitis found with BPH.