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Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats
Published on: November 20, 2015
[Perinatal outcome of pregnancies in advanced maternal age]
Anna Kristell Nolasco-Blé1, Ricardo Jorge Hernández-Herrera, René Mónico Ramos-González
1Instituto Mexicano del Seguro Social, Unidad Médica de Alta Especialidad número 23, Hospital de Gineco-Obstetricia Dr. Ignacio Morones Prieto, Monterrey, NL. kristellnolasco@hotmail.com
Background:
Traditionally an advanced maternal age have been associated with a higher risk of unfavorable perinatal results.
Objective:
to know the perinatal outcomes in women giving birth at age 40 or older during a year in a concentration hospital located at Monterrey, Nuevo León.
Patients And Methods:
In a retrospective, cross-sectional, study.
Results:
163 women and 170 newborn were included. A newborn death (5.8 x 1000 RN) and no one maternal death was observed. The most frequent maternal associated disease was gestational diabetes (16%) followed by the hypertensive disorders (10%). The cesarean rate was 71.1% and the most frequent indication was previous cesarean. The most frequent hospitalization cause was early premature labour (4.2%). Premature membrane was observed in 11% of patients. The mean delivery time was at 38 weeks with a mean body weight of 3032 g. There were 5 newborn with congenital malformations (2.9%). 21 newborns were hospitalized (12%) and the most frequent indication was prematurity.
Conclusion:
Women giving birth at age 40 or older observed a higher gestational diabetes incidence followed by the pregnancy-induced hypertension. The cesarean delivery was the most frequent mode of delivery. We consider that the perinatal outcomes in this study were favorable for both mother and child.
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