Pro/con debate: Is etomidate safe in hemodynamically unstable critically ill patients?
Related Experiment Video
Updated: May 20, 2026

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings
Published on: November 9, 2016
Abstract:
Etomidate is an induction agent known for its smooth intubating conditions and cardiovascular stability. Studies, however, have shown that a single dose of etomidate can result in a prolonged adrenal insufficiency. The impact of this in patients with sepsis has been a matter for debate. This review presents a pro/con case for using etomidate in hemodynamically unstable critically ill patients and provides guidance for alternative induction techniques and when the use of etomidate might be justified despite these concerns.
Related Concept Videos
Parenteral Anesthetics: Overview
Cardiopulmonary Resuscitation IV: Pharmacological Management
Stages of General Anesthesia
Skeletal Muscle Relaxants: Adverse Effects
Unlike...
Depolarizing Blockers: Pharmocokinetics
Cardiomyopathy VII: Pre and Post Operative Nursing Management