Osteolipoma presenting as a submandibular mass: a rare presentation
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Updated: May 20, 2026

Lateral Molar Approach-Driven Transoral Endoscopic Procedure for Benign Infratemporal Fossa Tumor Resection
Published on: August 15, 2025
Suzan Kavusi1, Vanda Farahmand, Terence M Davidson
1Department of Pathology, University of California, San Diego, 200 West Arbor Dr. #8720, San Diego, CA 92103-8720, USA. sukavusi@ucsd.edu
Abstract:
Osteolipomas are rare tumors, particularly in the head and neck region, in contrast to lipomas which are the most common benign neoplasms in this location. Osseous changes are benign and mainly occur in long-standing lipomas. Despite its rarity, this neoplasm has a characteristic histopathologic appearance with lamellar bony spicules within the mature adipose tissue. Of the 19 cases previously reported in the oropharyngeal area, only two were located in the submandibular region. We report the third case of submandibular osteolipoma, presenting as an asymptomatic mass in a middle-aged man. Our review of head and neck osteolipomas would be of particular interest to pathologists and head and neck surgeons, in order to avoid inappropriate treatment of an otherwise benign lesion.
