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Appendiceal mucocele diagnosed in patients with inflammatory bowel disease using endoscopic ultrasound
1Division of Gastroenterology and Hepatology, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
Abstract:
When a bulging appendiceal orifice is observed during surveillance colonoscopy, the possibility of appendiceal mucocele must be considered. Appendiceal mucocele is a rare group of lesions characterized by mucinous distension of the appendiceal lumen with the dangerous potential to rupture, resulting in the development of pseudomyxoma peritonei. Early recognition and diagnosis of appendiceal mucocele can prevent the dreaded complication of pseudomyxoma peritonei but it requires a high index of suspicion. Patients with inflammatory bowel disease are at increased risk for colorectal neoplasm but neoplasm of the appendix is infrequently reported. We report two of the first cases of appendiceal mucoceles diagnosed in patients with inflammatory bowel disease using endoscopic ultrasound.
Insights
Appendiceal mucoceles, rare lesions causing mucinous distension, require early diagnosis to prevent pseudomyxoma peritonei. Endoscopic ultrasound aided in diagnosing these rare appendiceal mucoceles in inflammatory bowel disease patients.
Area of Science:
- Gastroenterology
- Oncology
- Surgical Pathology
Background:
- Appendiceal mucocele is a rare appendiceal lumen distension by mucin.
- Rupture can lead to pseudomyxoma peritonei, a dangerous complication.
- Patients with inflammatory bowel disease (IBD) have increased colorectal neoplasm risk, but appendiceal neoplasm is infrequent.
Purpose of the Study:
- To highlight the importance of considering appendiceal mucocele in patients with inflammatory bowel disease.
- To report the use of endoscopic ultrasound in diagnosing appendiceal mucoceles in IBD patients.
Main Methods:
- Surveillance colonoscopy identified a bulging appendiceal orifice.
- Endoscopic ultrasound was utilized for diagnosis.
- Two cases of appendiceal mucoceles in IBD patients were analyzed.
Main Results:
- Appendiceal mucoceles were successfully diagnosed using endoscopic ultrasound in two IBD patients.
- Early recognition of appendiceal mucocele is crucial to prevent pseudomyxoma peritonei.
Conclusions:
- Appendiceal mucocele should be considered when a bulging appendiceal orifice is seen during colonoscopy, especially in IBD patients.
- Endoscopic ultrasound is a valuable tool for diagnosing appendiceal mucoceles.
- Prompt diagnosis and management can prevent the severe complication of pseudomyxoma peritonei.
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