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Related Experiment Video

Updated: May 20, 2026

Intrathecal Application of a Fluorescent Dye for the Identification of Cerebrospinal Fluid Leaks in Cochlear Malformation
06:59

Intrathecal Application of a Fluorescent Dye for the Identification of Cerebrospinal Fluid Leaks in Cochlear Malformation

Published on: February 29, 2020

Cochlear Dysfunction in Children following Cardiac Bypass Surgery.

Mona M El Ganzoury1, Terez B Kamel, Lobna H Khalil

  • 1Department of Pediatrics, Ain Shams University, Cairo, Egypt.

ISRN Pediatrics
|July 20, 2012
PubMed
Summary

Moderate hypothermia during pediatric open-heart surgery may cause subtle cochlear dysfunction. Otoacoustic emissions testing can detect early hearing changes in these children.

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Area of Science:

  • Otorhinolaryngology
  • Pediatric Cardiology
  • Anesthesiology

Background:

  • Sensorineural hearing loss is a risk following procedures involving extracorporeal circulation and hypothermia.
  • While mild hypothermia may protect the cochlea, deep hypothermia can cause injury.
  • Auditory function assessment is crucial in children undergoing cardiac surgery.

Purpose of the Study:

  • To evaluate auditory function in children post-open-heart surgery.
  • To compare the effects of mild versus moderate hypothermia on cochlear health.
  • To identify potential risks of different hypothermic techniques on hearing.

Main Methods:

  • Forty children with acyanotic heart disease were divided into two groups: mild hypothermia (33-37°C) and moderate hypothermia (28-32°C).

Related Experiment Videos

Last Updated: May 20, 2026

Intrathecal Application of a Fluorescent Dye for the Identification of Cerebrospinal Fluid Leaks in Cochlear Malformation
06:59

Intrathecal Application of a Fluorescent Dye for the Identification of Cerebrospinal Fluid Leaks in Cochlear Malformation

Published on: February 29, 2020

  • Audiological assessments included basic evaluations and otoacoustic emissions testing (distortion-product and transient evoked).
  • Comparative analysis of auditory function between the two hypothermia groups was performed.

    • Main Results:

    • Both groups showed distortion-product otoacoustic emissions (DPOAEs) amplitude >3 dB SPL.
    • The moderate hypothermia group exhibited lower DPOAE amplitudes, particularly at high frequencies.
    • Transient evoked otoacoustic emissions (TEOAEs) showed significantly more partial passes and reduced amplitude in the moderate hypothermia group.

    Conclusions:

    • Moderate hypothermic techniques in pediatric cardiac surgery are associated with subtle cochlear dysfunction.
    • Otoacoustic emissions are effective for early detection of subclinical cochlear impairment in these patients.
    • This highlights the importance of audiological monitoring after cardiac procedures involving moderate hypothermia.