Selective quenching of benzimidazole derivatives by Cu²+ metal ion

It is a very big challenge to develop a Cu(2+) selective fluorescent sensor with the ability to exclude the interference of some metal ions such as Fe(3+), Mg(2+), Ag(+), K(+) and Na(+). Herein, we report a fluorescence quenching of some benzimidazole derivatives (1-6) with Cu(2+) metal ion. These benzimidazole derivatives have been shown to bind copper ions resulting in quenching of its fluorescence. The response to Cu(2+) is rapid, selective and reversible upon addition of a copper chelator. These benzimidazole derivatives were characterized by (1)H, (13)C NMR mass and elemental analysis. XRD analysis was carried out for 1-(4-methylbenzyl)-2-p-tolyl-1H-benzo[d]imidazole.