Related Experiment Video
Updated: May 20, 2026
07:17
Automated Vibratome Sectioning of Agarose-Embedded Lung Tissue for Multiplex Fluorescence Imaging
Published on: October 6, 2023
Alveolar ridge preservation. A systematic review.
Attila Horváth1, Nikos Mardas, Luis André Mezzomo
1Unit of Periodontology, Department of Clinical Research, UCL Eastman Dental Institute, 256 Gray's Inn Road, London WC1X 8LD, UK.
Clinical Oral Investigations
|July 21, 2012
Summary
Alveolar ridge preservation (ARP) may limit post-extraction bone loss but does not eliminate it. Further research is needed to confirm its clinical benefits for implant placement.
Area of Science:
- Dental surgery
- Periodontology
- Oral implantology
Background:
- Alveolar ridge (AR) resorption after tooth extraction is a common clinical challenge.
- Alveolar ridge preservation (ARP) techniques aim to mitigate this bone loss.
Purpose of the Study:
- To systematically review the effects of alveolar ridge preservation (ARP) compared to unassisted socket healing.
Main Methods:
- Systematic review of randomized controlled trials (RCTs), controlled clinical trials (CCTs), and prospective cohort studies.
- Data synthesis focused on clinical, radiographic, and histological outcomes.
Main Results:
- ARP demonstrated statistically significant reductions in alveolar ridge width and height compared to controls in several studies.
- Histological analysis showed new bone formation in both groups, with some grafts interfering with healing.
- Less augmentation was needed for subsequent implant placement in ARP groups.
Conclusions:
- ARP can limit, but not eliminate, post-extraction alveolar ridge resorption.
- Histological evidence for enhanced new bone formation with ARP is inconsistent.
- Further RCTs comparing unassisted healing with ARP are required for definitive clinical guidance.
Related Concept Videos
01:26Alveoli and Alveolar Ducts
The respiratory zone of the human body, which stands in contrast to the conducting zone, comprises the structures that actively participate in the exchange of gases. The initiation of this zone is marked by the terminal bronchioles converging into respiratory bronchioles, the tiniest bronchiole classification. The respiratory bronchioles give way to the alveolar ducts that opens into a congregation of alveoli. Actively involved in gas exchange, alveoli resemble tiny sacs similar to clusters of...
01:10Atelectasis II: Pathophysiology
Atelectasis develops when alveoli lose their air and collapse inward. Because lung tissue is naturally elastic, these air sacs shrink rather than remaining open. Collapsed alveoli are no longer ventilated, reducing their role in gas exchange. Blood flow may continue in these regions, creating a ventilation–perfusion mismatch. Clinical findings include decreased breath sounds, dullness to percussion, reduced chest expansion, and decreased tactile fremitus as sound transmission through collapsed...
01:26COPD: Management Using Bronchodilators and Corticosteroids
Chronic obstructive pulmonary isease (COPD) involves a group of progressive lung disorders characterized by persistent airflow limitation and chronic respiratory symptoms. Asthma-COPD Overlap Syndrome (ACOS), encompassing features of both asthma and Chronic obstructive pulmonary disease (COPD), is a group of progressive lung disorders that includes chronic bronchitis, emphysema, and refractory (non-reversible) asthma. ACOS leads to complex clinical presentations that combine the inflammatory...
01:21Acute Respiratory Failure-II
Type I Respiratory Failure, or hypoxemic respiratory failure, occurs when the partial pressure of oxygen (PaO2) in arterial blood falls below 60 mmHg while breathing room air without a corresponding increase in arterial carbon dioxide levels (PaCO2). This condition highlights a significant impairment in the lungs' capacity to oxygenate the blood.
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
01:18Respiratory Regulation of Acid-Base Balance
Respiratory compensation is a vital physiological process that stabilizes blood plasma pH by regulating the partial pressure of carbon dioxide (PCO2), a key determinant of pH levels. Most carbon dioxide in the blood dissolves and converts into carbonic acid (H2CO3). It dissociates into hydrogen ions (H+) and bicarbonate ions (HCO3⁻). There is also an inverse relationship between PCO2 and pH.
When carbon dioxide levels increase in the blood, more H+ and HCO3⁻ are produced, leading to a...
When carbon dioxide levels increase in the blood, more H+ and HCO3⁻ are produced, leading to a...
01:23Chronic Obstructive Pulmonary Disease II: Emphysema
Emphysema, a major phenotype of chronic obstructive pulmonary disease (COPD), is characterized by irreversible destruction of alveolar walls and permanent enlargement of distal airspaces. Unlike chronic bronchitis, which primarily affects the airways, emphysema predominantly involves the lung parenchyma, where structural damage leads to airflow limitation.PathophysiologyIt most commonly results from prolonged exposure to cigarette smoke and other toxic gases, particularly cigarette smoke.