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Updated: May 20, 2026

Destabilization of the Medial Meniscus and Cartilage Scratch Murine Model of Accelerated Osteoarthritis
Published on: July 6, 2022
Experimental morphological study of the effects of subchondral tunnelization and bone marrow stimulation on articular
T A Stupina1, V D Makushin, M A Stepanov
1G. A. Ilizarov Russian Research Center Reparative Traumatology and Orthopedics, Rosmedtechnologies, Kurgan, Russia. StupinaSTS@mail.ru
Abstract:
The articular cartilage was studied under conditions of experimental osteoarthrosis with tunnelization of the subchondral zone and injection of autologous bone marrow into the channels. Histomorphological studies showed that tunnelization of the subchondral zone with injection of autologous bone marrow into the channels stimulated reparative regeneration of the chondral tissue by inhibiting destruction of the joints.
