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Updated: May 20, 2026

Enhanced Oil Recovery using a Combination of Biosurfactants
Published on: June 3, 2022
Synthesis, self-aggregation and bioactivity properties of a cationic aminoacyl surfactant, based on a new class of
Luca Simeone1, Carlo Irace, Antonio Di Pascale
1Dipartimento di Scienze Chimiche, Università di Napoli "Federico II", Complesso Universitario di Monte S. Angelo, via Cintia, 4, I-80126 Napoli, Italy.
Abstract:
A highly functionalized aminoacyl nucleolipid based on uridine is here proposed as a novel cationic surfactant. To achieve this, a straightforward, high yielding and versatile protocol has been devised, in principle providing synthetic access to a variety of different, related analogs. Self-aggregation properties of this nucleolipid were determined by using a combined approach, including surface tension, conductivity and DLS measurements. Above the critical micellar concentration of 4 × 10(-5) mol kg(-1), large supramolecular assemblies with a counterion condensation degree of 0.25 were observed. The bioactivity profile of this new compound was investigated on cancer and non cancer cell lines.
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