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Intrauterine insemination in subfertile couples
1Institute for the Study of Fertility Serlin Maternity Hospital, Tel-Aviv Medical Centre, Sackler School of Medicine, Tel Aviv University, Israel.
Andrologia
|January 1, 1990
Summary
Intrauterine insemination (IUI) shows effectiveness in treating cervical factor infertility, achieving a 42.8% pregnancy rate. However, its value is questionable for subfertile sperm quality or unexplained infertility cases.
Area of Science:
- Reproductive Medicine
- Infertility Treatment
Background:
- Subfertility affects numerous couples globally.
- Intrauterine insemination (IUI) is a common assisted reproductive technology.
- Understanding IUI's efficacy across different infertility causes is crucial.
Purpose of the Study:
- To evaluate the effectiveness of intrauterine insemination (IUI) with washed sperm.
- To compare IUI success rates in women with cervical factor infertility, subfertile sperm quality, and unexplained infertility.
Main Methods:
- A cohort of 43 subfertile women underwent IUI with washed sperm.
- Ovulation was managed spontaneously or with clomiphene citrate or hMG-hCG.
- 167 inseminations were performed across 90 ovulatory cycles.
Main Results:
- An overall pregnancy rate of 14% (6/43) was observed.
- Pregnancy rates varied significantly by infertility cause: 42.8% for cervical factor, 11.7% for low sperm quality, and 5.2% for unexplained infertility.
Conclusions:
- Intrauterine insemination (IUI) is a highly effective treatment for cervical factor infertility.
- The efficacy of IUI is less certain for cases involving subfertile sperm quality or unexplained infertility.