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Related Concept Videos

Rheumatic Heart Disease III: Medical Management01:21

Rheumatic Heart Disease III: Medical Management

Rheumatic heart disease (RHD) management can be divided into two main strategies: prevention and long-term management.Primary PreventionPrimary prevention focuses on timely diagnosis and management of group A streptococcal pharyngitis to prevent acute rheumatic fever. The most widely used antibiotic for treating this condition is intramuscular benzathine penicillin G.Acute Rheumatic Fever TreatmentThe primary treatment goal for a patient diagnosed with acute rheumatic fever is to suppress the...
Rheumatic Heart Disease IV: Nursing Management01:20

Rheumatic Heart Disease IV: Nursing Management

AssessmentA comprehensive assessment is essential in managing a patient with rheumatic heart disease (RHD). Begin with obtaining a detailed medical history, including recent streptococcal infections, a history of rheumatic fever, or previously diagnosed rheumatic heart disease. Assess the patient for symptoms such as fever, chest pain, widespread joint pain (arthralgia), tachycardia, pericardial friction rub, muffled heart sounds, heart murmurs, peripheral edema, subcutaneous nodules, and...
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Rheumatic Heart Disease I: Introduction

Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
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Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies01:22

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
Transmission-based Precautions I: Contact, Enteric, and Droplets01:17

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Transmission-based precautions are for patients known to be infected or suspected to be infected or colonized with organisms that pose a significant risk to others. Some transmission-based precautions include contact, enteric, and droplet.
Contact Precautions:
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Preliminary Study on Acupuncture Combined with Grain-sized Moxibustion for Treating Rheumatoid Arthritis with Finger Joint Pain
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Tight disease control in early RA.

Deepali Sen1, Richard Brasington

  • 1Division of Rheumatology, Department of Medicine, Washington University School of Medicine, 660 South Euclid Avenue, St Louis, MO 63110, USA. dsen@dom.wustl.edu

Rheumatic Diseases Clinics of North America
|July 24, 2012
PubMed
Summary
This summary is machine-generated.

Aggressive treatment for early rheumatoid arthritis (RA) using treat-to-target strategies improves long-term outcomes. This review examines studies on early RA management, including oral and biologic therapies, focusing on achieving remission.

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Area of Science:

  • Rheumatology
  • Clinical Medicine
  • Pharmacology

Background:

  • Growing evidence supports aggressive intervention for early rheumatoid arthritis (RA).
  • Treat-to-target strategies in RA management yield superior long-term results.
  • Both oral disease-modifying antirheumatic drugs (DMARDs) and biologic agents are effective for early RA.

Purpose of the Study:

  • To review studies on early rheumatoid arthritis treatment.
  • To focus on the treat-to-target approach in managing early RA.
  • To evaluate the effectiveness of different therapeutic strategies in early active RA.

Main Methods:

  • Literature review of studies on early rheumatoid arthritis treatment.
  • Analysis of research employing treat-to-target strategies.
  • Comparison of various therapeutic interventions, including oral DMARDs and biologics.

Main Results:

  • Treat-to-target strategies demonstrate superior long-term outcomes in early RA.
  • Oral DMARDs and biologic agents show efficacy in treating early RA.
  • Ongoing research is needed to clarify optimal initial therapy for early active RA.

Conclusions:

  • Aggressive therapeutic intervention is beneficial for early rheumatoid arthritis.
  • Treat-to-target strategies are effective for achieving low disease activity or remission in RA.
  • Further research is required to determine the most effective initial treatment for early active RA.