Polyhistidine triad proteins of pathogenic streptococci

Charles D Plumptre1, Abiodun D Ogunniyi, James C Paton

  • 1Research Centre for Infectious Diseases, School of Molecular and Biomedical Science, University of Adelaide, SA, 5005, Australia.

Summary

Polyhistidine triad (Pht) proteins on Streptococcus pneumoniae are key virulence factors and vaccine candidates. These surface proteins also play roles in metal ion balance and bacterial adherence.

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