Related Experiment Video
Updated: May 20, 2026

Preparation and In Vitro Characterization of Dendrimer-based Contrast Agents for Magnetic Resonance Imaging
Published on: December 4, 2016
Comparing anisotropic diffusion filters for the enhancement of sodium magnetic resonance images
Christoph M Decker1, Frank G Zöllner, Simon Konstandin
1Computer Assisted Clinical Medicine, Medical Faculty Mannheim, Heidelberg University, 68167 Mannheim, Germany.
Abstract:
The anisotropic diffusion (AND) filter, an image processing technique derived from physics, was applied to low-resolution sodium magnetic resonance imaging (MRI) to examine the possibilities of image enhancement by postprocessing. We compared six different variants of AND filters. Besides the qualitative good results on phantom measurements, quantitative analyses on MRI of human kidney yielded major improvements in noise reduction and other quality measures: the noise (i.e., the standard deviation in the image background) could be reduced to 1%-2% of its original value, while linear filters (Gaussian, Fermi, Hamming) achieved a reduction to 42%-64%. Besides that, less than 5% of structures and intensities are lost when using AND filters. Comparing the different variants, the two-dimensional and the three-dimensional AND filter outperformed the histogram-of-gradient and tensor-based AND filter. We envision that by using these AND filters, quantitative analysis of sodium MRI of kidney could be improved.
Related Concept Videos
Magnetic Resonance Imaging
Double Resonance Techniques: Overview
Spin decoupling is usually achieved by...
NMR Spectrometers: Resolution and Error Correction
NMR Spectrometers: Radiofrequency Pulses and Pulse Sequences
¹H NMR: Interpreting Distorted and Overlapping Signals
As Δν decreases and the signals move closer, the doublets appear increasingly distorted. The intensities of the inner lines increase at the cost of those of the outer lines as the signals are slanted or...
Insensitive Nuclei Enhanced by Polarization Transfer (INEPT)

