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Updated: May 20, 2026

Multidimensional Coculture System to Model Lung Squamous Carcinoma Progression
Published on: March 17, 2020
Squamous-cell carcinoma of the lungs: is it really so different?
María Sereno1, Isabel Rodríguez Esteban, Francisco Zambrana
1Medical Oncology Department, University Infanta Sofía Hospital, San Sebastian de los Reyes, Madrid, Spain. mariasereno75@gmail.com
Background:
Squamous cell carcinoma (SCC) is the predominant histological type in men, and adenocarcinoma is the most common subtype in women in the world. The incidence of SCC is decreasing in men, while the incidence of adenocarcinoma (AC) is stable or slightly increasing in western countries. There is active research on the AC subtype but SCC remains poorly studied.
Conclusions:
In this review, we have studied different aspects of the SCC subtype, including epidemiology, clinical features, pathology, molecular biology markers, and new therapeutic targets, treatments and prognosis implications.
