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Updated: May 20, 2026

Quantifying Cognitive Decrements Caused by Cranial Radiotherapy
Published on: October 18, 2011
[SMART syndrome: case report of a rare complication after cerebral radiation therapy]
P Truntzer1, A Monjour, C Gaultier
1Service de radiothérapie, centre Paul-Strauss, Porte-de-l'Hôpital, Strasbourg, France. pierre.truntzer@laposte.net
Abstract:
The authors report a 71-year-old woman case who developed, 7 years after a cerebral radiation therapy for a parietooccipital glioblastoma, a stroke-like migraine attacks after radiotherapy syndrome (SMART syndrome), a rare complication characterized by reversible neurologic deficits with migraine described after cerebral irradiation. Transient gyriform reversible enhancement is found on MRI during crises. This case report allows discussing the clinical, iconographic presentation and the clinical outcome of this syndrome at the light of the literature publication.
