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Updated: May 20, 2026

Preparation of a Blood Culture Pellet for Rapid Bacterial Identification and Antibiotic Susceptibility Testing

Preparation of a Blood Culture Pellet for Rapid Bacterial Identification and Antibiotic Susceptibility Testing

Published on: October 15, 2014

Update on bloodstream infections in ICUs.

Jean-Francois Timsit¹, Kevin B Laupland

¹Integrated Research Center U823, Albert Bonniot Institute, University Grenoble 1, La Tronche, France. jftimsit@chu-grenoble.fr

Current Opinion in Critical Care

|July 24, 2012

Summary

Bloodstream infections (BSIs) in intensive care units (ICUs) are increasing, particularly healthcare-associated BSIs. Rising antimicrobial resistance poses a significant threat to treatment success in critically ill patients.

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Area of Science:

Infectious Diseases
Critical Care Medicine
Epidemiology

Background:

Patient demographics in ICUs are shifting towards older individuals with complex comorbidities.
Healthcare-associated bloodstream infections (BSIs) are increasingly recognized as a distinct and significant category within ICUs.
The epidemiology and outcomes of BSIs in ICUs are evolving due to these changing patient populations and infection patterns.

Purpose of the Study:

To review and describe recent advancements in understanding the epidemiology of BSIs in intensive care units (ICUs).
To analyze the current outcomes associated with BSIs in critically ill patients.
To highlight emerging trends in antimicrobial resistance related to BSIs.

Main Methods:

Literature review of recent developments in BSI epidemiology and outcomes in ICUs.
Analysis of data on patient demographics, infection types (community-onset healthcare-associated, community-acquired, nosocomial), and resistance patterns.
Evaluation of the impact of electronic surveillance systems on BSI tracking and resistance monitoring.

Main Results:

The incidence of BSIs in ICUs is influenced by an increasing proportion of elderly patients with multiple comorbidities.
Community-onset healthcare-associated BSIs are a notable cause of infections in ICUs, differing from traditional community-acquired and nosocomial infections.
Evolving electronic surveillance systems offer improved efficiency in monitoring BSI occurrence and tracking antimicrobial resistance.

Conclusions:

Healthcare-associated BSIs are rising and frequently involve bacteria resistant to common antimicrobials.
The emergence of extensively drug-resistant bacteria globally presents major challenges for antimicrobial therapy failure.
There is a critical need for enhanced preventive strategies and optimized treatment protocols to mitigate the burden of BSIs and curb further resistance development in ICUs.