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Updated: May 20, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
[An update on the secondary prevention of cerebral infarction due to atrial fibrillation]
Fernando Barinagarrementeria Aldatz1
1División de Ciencias de la Salud, Universidad del Valle de México, Hospital Ángeles de Querétaro, Querétaro, Qro. fbarinaga@prodigy.net.mx
Abstract:
Stroke is the second most common cause of death in the world and produces a high number of cases with neurological dysfunction. Atrial fibrillation (AF) is the main risk factor in patients with cardioembolic stroke. In Mexico, there are approximately 850,000 patients with AF. In three stroke and TIA Mexican series including 3,194 patients, the frequency of AF in cases of stroke and TIA were 12.5 and 8.1%, respectively. AF increase stroke risk in six times. Different approaches to AF detection in stroke patients have been postulated. Besides electrocardiogram, non-invasive cardiac monitoring is useful for AF detection. Is very important to detect particular subgroups with high risk of paroxysmal AF, including those with cryptogenic stroke. Is important to stratify the risk of stroke in patients with AF. More than a dozen of scales have been proposed. CHADS2 is one of the most commonly used, and recently another one has been proposed (CHA2DS2-VASc). Warfarin has been successfully used in stroke prevention in AF. However need of coagulation monitoring as well diet and drugs restriction limit their use. New oral anticoagulants without these restrictions as well low rates of hemorrhagic complications are now available.
Insights
Atrial fibrillation (AF) significantly increases stroke risk. Early detection and risk stratification are crucial for preventing strokes in AF patients, with new oral anticoagulants offering improved safety and convenience.
Area of Science:
- Cardiology
- Neurology
- Public Health
Context:
- Stroke is a leading global cause of death and disability.
- Atrial fibrillation (AF) is a primary risk factor for cardioembolic stroke.
- Mexico has a substantial population affected by AF, estimated at 850,000.
Purpose:
- To highlight the importance of Atrial Fibrillation (AF) detection in stroke patients.
- To discuss risk stratification strategies for stroke in AF patients.
- To review current and emerging anticoagulation therapies for stroke prevention in AF.
Summary:
- Atrial fibrillation (AF) increases stroke risk sixfold, with significant prevalence in Mexican stroke and TIA cohorts (12.5% and 8.1%).
- Non-invasive cardiac monitoring aids in detecting AF, especially paroxysmal AF in cryptogenic stroke.
- Risk scores like CHADS2 and CHA2DS2-VASc aid in stratifying stroke risk in AF patients.
Impact:
- Improved identification of high-risk individuals for timely intervention.
- Enhanced stroke prevention strategies through effective AF management.
- Facilitation of informed clinical decisions regarding anticoagulation therapy, including newer agents.
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