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Feedback Loops

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In most cases, excessive hormone production is prevented by negative feedback—a loop that starts with a stimulus inducing the release of a particular substance, like a hormone, to maintain a certain level before triggering a signal that results in a decrease in further release of the hormone.

Journal Bearings

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Journal bearings are mechanical components that support and provide lateral stability to rotating shafts and axles. They are crucial in reducing friction, wear, and vibration in machinery such as engines, turbines, and pumps. The principle behind journal bearings is forming a thin lubricant film between the bearing surface and the rotating shaft, which minimizes direct contact and reduces frictional forces.
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Feedback Inhibition

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Proofreading

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Proofreading

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Synthesis of new DNA molecules is carried out by the enzyme DNA polymerase, which adds nucleotides on the daughter strand complementary to the template DNA strand. DNA polymerase has a higher affinity to add the correct base and ensures fidelity during DNA replication. Furthermore, it exhibits proofreading activity during replication, using an exonuclease domain that cuts off incorrect nucleotides from the nascent DNA strand.
Errors During Replication are Corrected by the DNA Polymerase Enzyme

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Related Experiment Video

Updated: May 20, 2026

Perspectives on Neuroscience

Perspectives on Neuroscience

Published on: July 31, 2007

Letters to the editor

A Fukushima¹, H Ueno, A Kijlstra

¹Department of Ophthalmology, Kochi Medical School, Nankoku, Kochi, 783, Japan, 0888-66-2194, fax; 0888-66-2194.

Ocular Immunology and Inflammation

|July 25, 2012

Summary

No abstract available in PubMed .

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