Recurrent uveitis, cystoid macular edema and pericarditis in Lyme disease

Y Guex-Crosier1, C P Herbort

  • 1Hôpital Ophtalmique Jules Gonin, Department of Ophthalmology, University of Lausanne, Lausanne, Switzerland.

Insights

Lyme disease can cause serious systemic and ocular issues, including pars planitis and pericarditis. Prompt antibiotic treatment for Borrelia burgdorferi infection led to sustained symptom resolution in a patient with these complications.

Area of Science:

  • Ophthalmology
  • Infectious Diseases
  • Cardiology

Background:

  • Lyme disease, caused by Borrelia burgdorferi, is known for diverse systemic and ocular manifestations.
  • Pars planitis and pericarditis are rare but documented complications of Lyme disease.

Purpose of the Study:

  • To report a case of recurrent pars planitis and acute pericarditis potentially linked to Lyme disease.
  • To highlight the diagnostic challenges and treatment efficacy for Lyme disease-associated complications.

Main Methods:

  • A case study of a 26-year-old male patient presenting with recurrent pars planitis and pericarditis.
  • Comprehensive medical investigations, including a western blot for Borrelia burgdorferi.
  • Treatment with specific antibiotics for Lyme disease.

Main Results:

  • Patient exhibited recurrent pars planitis and two episodes of acute pericarditis.
  • Extensive workup was negative except for a highly positive western blot for Borrelia burgdorferi.
  • Antibiotic therapy resulted in a prolonged period without relapse.

Conclusions:

  • Lyme disease should be considered in the differential diagnosis of patients with recurrent pars planitis and pericarditis.
  • Early and specific antibiotic treatment can effectively manage these systemic and ocular complications.
  • This case underscores the importance of thorough investigation for infectious etiologies in complex presentations.

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