Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Case Studies01:22

Case Studies

There are many research methods available to psychologists in their efforts to understand, describe, and explain behavior and the cognitive and biological processes that underlie it.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

REcanalization of Distal Cerebral Vessels In Acute Stroke Using ApeRio (REVISAR).

Journal of neurointerventional surgery·2025
Same author

Advanced imaging reveals enhanced malignancy in glioblastomas involving the subventricular zone: evidence of increased infiltrative growth and perfusion.

Journal of neuro-oncology·2024
Same author

Cerebral blood flow from arterial spin labeling as an imaging biomarker of outcome after endovascular therapy for ischemic stroke.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism·2024
Same author

High relative cerebral blood volume is associated with good long term clinical outcomes in acute ischemic stroke: a retrospective cohort study.

BMC neurology·2024
Same author

Exploring molecular glioblastoma: Insights from advanced imaging for a nuanced understanding of the molecularly defined malignant biology.

Neuro-oncology advances·2024
Same author

Reproducibility of CT-based opportunistic vertebral volumetric bone mineral density measurements from an automated segmentation framework.

European radiology experimental·2024

Related Experiment Video

Updated: May 20, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
10:39

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

Published on: June 2, 2014

A case-control study on cortical thickness in episodic cluster headache.

Christian L Seifert1, Stefano Magon, Kathrin Staehle

  • 1Department of Neurology, Technische Universität München, Germany. c.seifert@lrz.tu-muenchen.de

Headache
|July 25, 2012
PubMed
Summary

Cluster headache patients show reduced cortical thickness in specific brain areas compared to controls. These changes may indicate brain plasticity related to the disorder, but their cause remains unclear.

More Related Videos

Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study
07:30

Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study

Published on: August 18, 2020

Dural Stimulation and Periorbital von Frey Testing in Mice As a Preclinical Model of Headache
05:40

Dural Stimulation and Periorbital von Frey Testing in Mice As a Preclinical Model of Headache

Published on: July 29, 2021

Related Experiment Videos

Last Updated: May 20, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
10:39

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

Published on: June 2, 2014

Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study
07:30

Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study

Published on: August 18, 2020

Dural Stimulation and Periorbital von Frey Testing in Mice As a Preclinical Model of Headache
05:40

Dural Stimulation and Periorbital von Frey Testing in Mice As a Preclinical Model of Headache

Published on: July 29, 2021

Area of Science:

  • Neuroimaging
  • Neurology
  • Brain Anatomy

Background:

  • The exact cause of cluster headache remains unknown, though hypothalamic dysfunction is suspected.
  • Previous research on other pain conditions like migraine shows cortical thickness changes.
  • No prior studies have investigated cortical thickness in cluster headache patients.

Purpose of the Study:

  • To investigate differences in cortical thickness between cluster headache patients and healthy individuals.
  • To explore the relationship between disease duration and cortical thickness in cluster headache.

Main Methods:

  • 12 episodic cluster headache patients (without acute attacks) and matched healthy controls underwent high-resolution 3T MRI.
  • A whole-brain surface-based comparison of cortical thickness was performed.
  • Correlation analysis examined the relationship between disease duration and cortical thickness.

Main Results:

  • Cluster headache patients exhibited reduced cortical thickness in the angular and precentral gyri, contralateral to the headache side.
  • These specific cortical thickness reductions did not correlate with disease duration.
  • A region within the primary sensory cortex showed a correlation between cortical thickness and disease duration.

Conclusions:

  • Cortical thickness alterations in cluster headache patients suggest a role for cortical structures in the condition's development.
  • It is undetermined whether observed cortical changes are a cause or consequence of cluster headache.
  • Disease-related plasticity in the somatosensory system is suggested by the correlation between somatosensory cortex thickness and disease duration.