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Updated: May 20, 2026

Self-assembling Morphologies Obtained from Helical Polycarbodiimide Copolymers and Their Triazole Derivatives
Published on: February 7, 2017
Formation of higher-order structures of chiral poly(ethynylpyridine)s depending on size, temperature, and saccharide
Hajime Abe1, Kotaro Okada, Hiroki Makida
1Graduate School of Pharmaceutical Sciences, University of Toyama, Sugitani 2630, Toyama, Toyama 930-0194, Japan. abeh@pha.u-toyama.ac.jp
Abstract:
Amphiphilic 2,6-pyridylene ethynylene "meta-ethynylpyridine" polymers having chiral oligo(oxyethylene) side chains were developed as hosts for saccharide recognition. The polymers were prepared via a Sonogashira reaction and fractionated by gel permeation chromatography (GPC). They showed circular dichroism (CD) activity due to their higher-order chiral helical structures, and their CD and UV-vis spectra changed depending on not only saccharide recognition but also molecular size, temperature, and metal cation recognition.
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