Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Glucocorticoid therapy in hyperandrogenism.

E Steinberger, L J Rodriguez-Rigau, S M Petak

    Bailliere'S Clinical Obstetrics and Gynaecology
    |September 1, 1990
    PubMed
    Summary

    Idiopathic glucocorticoid-suppressible hyperandrogenism (IGSH) in women improves with glucocorticoid therapy, normalizing androgen levels and enhancing ovulatory function. This treatment effectively manages symptoms and infertility associated with hyperandrogenism.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Effectiveness of person-centred versus usual care in elderly patients: findings from a multicentre randomised controlled trial.

    Journal of pharmaceutical policy and practice·2026
    Same author

    Video vignette: incisional perineal hernia repair-perineal approach.

    Techniques in coloproctology·2024
    Same author

    Factors associated with negative <sup>99m</sup>Tc-MIBI scanning in patients with primary hyperparathyroidism.

    Revista espanola de medicina nuclear e imagen molecular·2021
    Same author

    Effect of the use of an iPad on the attention span of a child with Smith Magenis Syndrome: A single case study.

    Journal of intellectual disabilities : JOID·2021
    Same author

    Investigation of fibrillin microfibrils in the canine cruciate ligament in dogs with different predispositions to ligament rupture.

    Research in veterinary science·2020
    Same author

    Rise in differentiated thyroid cancer incidence in our hospital is not related with an increased incidental microcarcinoma detection.

    Revista clinica espanola·2016

    Area of Science:

    • Endocrinology
    • Reproductive Medicine
    • Dermatology

    Background:

    • Hyperandrogenism is a common endocrine disorder in reproductive-aged females.
    • It presents with cutaneous manifestations and ovulatory dysfunction, often leading to infertility.
    • Idiopathic glucocorticoid-suppressible hyperandrogenism (IGSH) is the most frequent form.

    Purpose of the Study:

    • To investigate the efficacy of glucocorticoid therapy in managing hyperandrogenism and its associated symptoms.
    • To evaluate the impact of glucocorticoid treatment on ovulatory function and fertility in women with IGSH.
    • To assess the long-term effects and safety of glucocorticoid therapy for IGSH.

    Main Methods:

    • Management of IGSH using physiological doses of glucocorticoids.

    Related Experiment Videos

  • Monitoring of serum androgen levels, cutaneous symptoms, and ovulatory function.
  • Assessment of pregnancy rates in relation to androgen suppression levels.

    • Main Results:

    • Glucocorticoid therapy normalized serum androgen levels, improved cutaneous symptoms, and enhanced ovulatory function.
    • Pregnancy occurrence in infertile women correlated with the degree of androgen suppression.
    • Physiological doses of glucocorticoids showed minimal side-effects and allowed for sustained normal androgen levels, even after treatment cessation.

    Conclusions:

    • Glucocorticoid therapy is an effective treatment for IGSH, addressing both hormonal imbalances and clinical manifestations.
    • The treatment corrects the hyperandrogenic state, thereby improving ovulatory function and fertility.
    • Long-term management with glucocorticoids is safe and effective for maintaining normal androgen levels indefinitely.