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Updated: May 20, 2026

In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography
Published on: July 24, 2020
Intraoperative spectral-domain optical coherence tomography in coats' disease
Christopher R Henry1, Audina M Berrocal, Ditte J Hess
1Bascom Palmer Eye Institute, Department of Ophthalmology, University of Miami Miller School of Medicine, Florida, USA.
Abstract:
The authors describe the spectral-domain optical coherence tomography findings in three patients undergoing examinations under anesthesia for treatment of Coats' disease. Patients were treated using a multifaceted approach of intravitreal bevacizumab and indirect diode laser vascular ablation. A handheld, portable spectral-domain optical coherence tomography system was used as a novel and critical intraoperative tool in differentiating Coats' disease from diffuse retinoblastoma and other simulating conditions and to monitor reductions in subretinal and intraretinal exudation during the course of treatment.

