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Updated: Sep 21, 2026

11:50
Enrichment for Chemoresistant Ovarian Cancer Stem Cells from Human Cell Lines
Published on: September 10, 2014
[In vitro drug-resistance decrease of ovarian cancer cells]
1Affiliated Obstetrics and Gynecology Hospital, Zhejiang Medical University, Hangzhou.
Zhonghua Fu Chan Ke Za Zhi
|November 1, 1990
Abstract:
A chemosensitivity test for ovarian cancer using tritiated thymidine incorporation assay was carried out. A dose-response relationship was observed for cis-platinum and an 5-fold increase of concentration converted the drug resistant tumor into a drug-sensitive one. Verapamil was found to enhance the cytotoxic effect of vincristine against ovarian cancer cells. It is suggested that combination of vincristine with verapamil may be helpful in treating some vincristine-resistant cases.

