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Multidisciplinary Approach to Obesity Management: A Case Report
Published on: May 30, 2025
Enuresis--an unattended comorbidity of childhood obesity
Y Weintraub1, S Singer, D Alexander
1Pediatric Endocrine and Diabetes Unit, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Ramat Gan, Israel. dryaelw@gmail.com
Insights
Obese children have a significantly higher risk of enuresis (bedwetting). This finding suggests enuresis should be a key consideration when evaluating obese youth.
Area of Science:
- Pediatrics
- Obesity Research
- Urology
Background:
- Obesity is increasingly prevalent in children and adolescents.
- Obstructive sleep apnea (OSA), attention deficit/hyperactivity disorder (ADHD), type 2 diabetes mellitus, and psychopathological issues are more common in obese and enuretic children.
- The relationship between childhood obesity and enuresis requires further investigation.
Purpose of the Study:
- To investigate the hypothesis that the prevalence of enuresis is increased in obese children and adolescents.
- To identify risk factors associated with enuresis in a pediatric population.
Main Methods:
- A cross-sectional study was conducted involving 281 children and adolescents aged 7-18 years.
- Participants completed questionnaires on enuresis, medical conditions, and sociodemographic parameters.
- Subjects were categorized into normal weight (n=158), overweight (n=37), and obese (n=86) based on BMI percentiles.
Main Results:
- Enuresis prevalence was significantly higher in obese (30%) and overweight (16%) youth compared to normal weight (8.8%) youth.
- Obesity was associated with a 6.5-fold increased odds of enuresis (OR=6.5, P<0.0001).
- Increased BMI-Z score, male gender, family history of enuresis, voiding dysfunction, and ADHD were associated with higher enuresis risk.
Conclusions:
- Obese children and adolescents face an elevated risk of enuresis.
- Enuresis should be routinely assessed during the primary evaluation of obese pediatric patients.
Objective:
Obstructive sleep apnea (OSA), attention deficit/hyperactivity disorder (ADHD), type 2 diabetes mellitus and psychopathological problems co-occur at increased rates among both obese and enuretic children. We hypothesized that the prevalence of enuresis will be increased in obese children and adolescents.
Design:
A cross-sectional study.
Subjects:
281 children and adolescents aged 7-18 years, who completed a questionnaire regarding enuresis, medical conditions and sociodemographic parameters; 158 were normal weight, 37 overweight (85thBMI (body mass index)<95th percentiles) and 86 obese (BMI95th percentile).
Main Outcome Measure(S):
Occurrence of enuresis among obese children and adolescents.
Results:
Enuresis was reported in 14 (8.8%) normal weight, 6 (16%) overweight and 26 (30%) obese youth. Odds ratio (OR)=6.5, 95% confidence interval (CI)=2.67-15.78 for enuresis among obese compared with normal weight (P<0.0001). Each increment of one BMI-Z score unit was associated with an increased risk of enuresis, OR of 2.14, 95% CI (1.46-3.12), P=0.00008. Male gender (OR 2.84, 95% CI (1.10-5.58), P=0.028), first-degree relative with current/past enuresis (OR 4.24, 95% CI (1.62-11.08), P=0.003), voiding dysfunction symptoms (OR 3.067, 95% CI (1.05-9.00), P=0.041) and ADHD (OR 2.31, 95% CI (0.99-5.34), P=0.051) increased the risk of enuresis. OSA-related symptoms, academic achievements in school, sharing a bedroom, family size relative to number of rooms in home, parental education, family status and religious observance were not found to increase the risk for enuresis.
Conclusions:
Obese children are at increased risk for enuresis. Enuresis should be clarified during the primary workup of every obese child and adolescent.
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