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Related Concept Videos

Transmission-based Precautions II: Airborne and Protective Environment01:25

Transmission-based Precautions II: Airborne and Protective Environment

Transmission-based precautions are for patients infected or suspected to be infected (or colonized) with organisms posing a significant risk to others. The transmission precautions include airborne and protective environment precautions.
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...
Sputum Studies II: Culture and Sensitivity01:20

Sputum Studies II: Culture and Sensitivity

Description
Sputum culture and sensitivity is a medical procedure used to diagnose bacterial infections in the respiratory tract and select the most appropriate antibiotics for treatment. This process involves analyzing sputum samples of thick and opaque secretions produced in the lungs and airways. These samples are collected from patients and then sent to the laboratory for analysis.
The test can identify various pathogens responsible for respiratory infections, including Streptococcus,...
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Overview of Respiratory System

The respiratory system is a complex biological apparatus that facilitates the exchange of gases, specifically oxygen and carbon dioxide, between our bodies and the environment. This system plays a vital role in the physiological process of respiration, an essential function for sustaining life.
What is the Respiratory System?
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The Respiratory System01:16

The Respiratory System

The respiratory system is comprised of the organs that enable breathing. Air enters the nostrils and mouth, followed by the pharynx (throat) and larynx (voice box), which lead to the trachea (windpipe). In the thoracic cavity, the trachea splits into two bronchi that allow air to enter the lungs. The bronchi split into progressively smaller bronchioles and terminate in small groups of tiny sacs in the lungs called alveoli, where gas exchange occurs.
Types of Toxins01:36

Types of Toxins

Humans continually engage with an environment rich in potentially harmful chemicals. These are introduced to our bodies through inhalation, ingestion, or skin contact. These chemicals exist in various forms, such as air and environmental pollutants, agricultural chemicals, organic solvents, and heavy metals.
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Environmental pollutants like...
Bioreactor Controls-II01:18

Bioreactor Controls-II

In aerobic fermentations, oxygen is vital for microbial growth and metabolite production. Since air comprises only about 20% oxygen and the gas is poorly soluble in water—just 9 ppm at 20°C—supplying sufficient oxygen becomes a critical challenge, especially in high-demand processes like yeast growth or citric acid production. Even a fully saturated broth may offer only a few seconds of oxygen availability.To address this, sterile or scrubbed air is introduced into the fermentor via a sparger...

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Measuring Carbon Content in Airway Macrophages Exposed to Carbon-Containing Particulate Matters
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Culture systems: air quality.

Theodore Thomas1

  • 1Reproductive Technology Laboratory, Martha Jefferson Hospital, Charlottesville, VA, USA. Ted.thomas@mjh.org

Methods in Molecular Biology (Clifton, N.J.)
|July 26, 2012
PubMed
Summary

Poor laboratory air quality poses risks to human gametes and embryos. Understanding how contaminants enter the lab and culture system is crucial for protecting embryo development and improving IVF success rates.

Area of Science:

  • Reproductive science
  • Environmental health
  • In vitro fertilization (IVF)

Background:

  • Laboratory air quality is a significant, yet often overlooked, factor impacting human gamete and embryo viability.
  • Existing analytical methods assess air pollutants, but specific toxicant concentrations causing harm are not well-defined.
  • Contaminant pathways into incubators and culture media remain a critical knowledge gap.

Purpose of the Study:

  • To highlight the risks of poor laboratory air quality on human gametes and embryos.
  • To emphasize the need for understanding contaminant infiltration routes.
  • To advocate for improved laboratory design and management for better in vitro embryonic development.

Main Methods:

  • Review of analytical methods for air pollutant identification and measurement.

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  • Discussion of contaminant pathways from the laboratory environment to the embryo culture system.
  • Assessment of the impact of air quality on in vitro embryonic development.
  • Main Results:

    • Poor air quality is a recognized hazard to gametes and embryos in culture.
    • Specific toxicant levels causing embryotoxicity are not adequately defined.
    • Understanding contaminant infiltration is key to mitigating risks.

    Conclusions:

    • Mitigating the adverse effects of poor air quality requires understanding contaminant entry points.
    • Site-specific air quality assessment can inform laboratory design and management.
    • Strategies to minimize air contamination are essential for protecting in vitro embryonic development.