Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Retinal vessel responses to passive tilting.

R M Baer1, D W Hill

  • 1Moorfields Eye Hospital, London.

Eye (London, England)
|January 1, 1990
PubMed
Summary

Passive head-down tilting caused immediate changes in retinal vessel caliber in healthy individuals. Arterioles narrowed and venules widened, indicating a rapid autoregulatory response to altered ocular perfusion pressure.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A Single Dose of Ibuprofen Impacts IL-10 Response to 164-km Road Cycling in the Heat.

Research quarterly for exercise and sport·2022
Same author

Enhancement of pressure perturbations in ablation due to kinetic magnetized transport effects under direct-drive inertial confinement fusion relevant conditions.

Physical review. E·2018
Same author

Consumption of a high-fat meal was associated with an increase in monocyte adhesion molecules, scavenger receptors, and Propensity to Form Foam Cells.

Cytometry. Part B, Clinical cytometry·2016
Same author

Effects of exercise mode and participant sex on measures of anaerobic capacity.

The Journal of sports medicine and physical fitness·2014
Same author

Relationship between speed and time in running.

International journal of sports medicine·2011
Same author

Perforating injuries of the globe [abridged].

Proceedings of the Royal Society of Medicine·2010

Area of Science:

  • Ophthalmology
  • Physiology
  • Vascular Biology

Background:

  • Retinal vessel calibre changes may reflect autoregulation of ocular perfusion pressure.
  • Understanding these responses is crucial for diagnosing various ocular conditions.

Purpose of the Study:

  • To investigate the effect of passive head-down tilting on retinal vessel calibre in healthy individuals.
  • To assess the autoregulatory capacity of the retinal vasculature.

Main Methods:

  • Utilized a tilting table for passive head-down tilting (30 degrees) in healthy subjects.
  • Acquired red-free fundus photographs before, during, and after the tilting period.
  • Measured arteriolar and venular calibre at multiple sites.

Main Results:

  • Arterioles showed a significant early decrease in calibre (-3.1%, p < 0.001).
  • Venules exhibited a significant early increase in calibre (3.7%, p < 0.001).
  • These calibre changes were not sustained despite maintained elevated ocular perfusion pressure.

Conclusions:

  • Healthy individuals exhibit rapid, yet transient, autoregulatory changes in retinal vessel calibre upon postural alteration.
  • The retinal vasculature demonstrates a prompt response to changes in perfusion pressure, but this response may not be sustained.

Related Experiment Videos