The acyl-CoA binding protein is required for normal epidermal barrier function in mice

Maria Bloksgaard1, Signe Bek2, Ann-Britt Marcher2

  • 1Department of Biochemistry and Molecular Biology, University of Southern Denmark, DK-5230 Odense, Denmark; MEMPHYS-Center for Biomembrane Physics, University of Southern Denmark, DK-5230 Odense, Denmark.

Summary

Acyl-CoA binding protein (ACBP) is crucial for skin barrier function. ACBP deficiency in mice leads to altered stratum corneum lipids, increased water loss, and impaired skin health.

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